Pig Study Raises MAJOR Questions Of Dangers Of Combining Quercetin & Ivermectin

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In a 2003 paper called ‘Lethal quercetin-digoxin interaction in pigs’ by Wang et al, researchers were blindsided by sudden, unexpected deaths within minutes of Pgp substrate digoxin having been administered with quercentin (full report)

“The coadministration of 40 mg/kg quercetin significantly elevated the Cmax of digoxin by 413% and increased the AUC0-t by 170%. The results indicated that a very serious pharmacokinetic interaction occurred between quercetin and digoxin. The concomitant administration of digoxin and quercetin or quercetin-containing herbs and dietary supplement should be avoided.”

“Unexpectedly, within 30 min after drug administration, two of the three pigs receiving combined therapy died suddenly, and the third pig suffered from typical mild symptoms of acute digoxin intoxication i.e. anorexia, nausea and the symptoms lasted up to 5 h.”

“Quercetin significantly increased the mean serum concentration of digoxin at 20 min by 165%.”

The difference in peak serum concentration was 413% higher in the quercetin + digoxin group than the digoxin alone group (8.8 vs 1.72)

“In summary, quercetin significantly enhanced the absorption of digoxin in pigs, possibly through the inhibition of intestinal P-gp. Such interaction would cause serious adverse drug reaction clinically if quercetin and digoxin were concomitantly administered. It is suggested that concurrent use of quercetin or quercetin glycoside-containing herbs or dietary supplements with digoxin or other P-gp substrates should be avoided, otherwise close monitoring of the critical therapeutic drugs is required.”

This is very concerning given that ivermectin is also a P-gp substrate!

For more in this series:

Ivermectin Toxicity Playlist: https://odysee.com/@TimTruth:b/major-fertility-hit-ivermectin:a?lid=008d0c4c5527c12b317f6dee675b36cbe6f654b8

Studies Find Quercetin & Natto K2 INHIBIT P-Glycoprotein Thus Increasing Susceptibility To Ivermectin Toxicity